Research Article
Matrix Metalloproteinase-2 Promoter Genotype as a Marker of
Cutaneous T-Cell Lymphoma Early Stage
Table 1
Three promoter MMP-2 gene polymorphisms: patients with CTCL versus control subjects.
| | −1575/G |
| | Genotypes and alleles | GG (%) | GA (%) | AA (%) | P g | G | A | P a | | CTCL () | 48 (54) | 37 (42) | 4 (4) | 0.931 | 0.747 | 0.253 | 0.804 | | Controls () | 105 (53) | 82 (41) | 11 (6) | 0.737 | 0.263 |
| | −1306 C/T |
| | Genotypes and alleles | CC (%) | CT (%) | TT (%) | 0.492 | C | T | 0.853 | | CTCL () | 46 (52) | 41 (46) | 2 (2) | 0.747 | 0.253 | | Controls () | 105 (53) | 83 (42) | 10 (5) | 0.740 | 0.260 |
| | −790 T/G |
| | Genotypes and alleles | TT (%) | TG (%) | GG (%) | 0.091 | T | G | 0.258 | | CTCL () | 46 (52) | 39 (44) | 4 (4) | 0.736 | 0.264 | | Controls () | 100 (51) | 73 (37) | 25 (12) | 0.689 | 0.311 |
|
|
= P-value of a difference in genotype distribution
= P-value of a difference in allelic frequencies.
|
