Promoter Variant of <i>PIK3C3</i> Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients

<table>Principal component (PC) analysis including all cases and controls. A. shows the first PC (<svg height="7.1624999" id="M45" style="vertical-align:-0.11285pt" version="1.1" viewbox="0 0 8.7250004 7.1624999" width="8.7250004" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,7.1625)">
<g transform="translate(72,-66.27)">
<text transform="matrix(1,0,0,-1,-71.95,66.44)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑥</tspan>
</text>
</g>
</g>
</svg>-axis) versus the second PC (<svg height="9.8625002" id="M46" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 7.875 9.8625002" width="7.875" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.8625)">
<g transform="translate(72,-64.11)">
<text transform="matrix(1,0,0,-1,-71.95,66.45)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑦</tspan>
</text>
</g>
</g>
</svg>-axis) for each subject. Each dot represents one subject and is color-coded by self-reported ancestral background (AA : African-American, His : Hispanic American, EA : European-American).</table>

BioMed Research International

fig1

Figure 1

Figure 1: Promoter Variant of <i>PIK3C3</i> Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients 

BioMed Research International

Promoter Variant of PIK3C3 Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients

Figure 1