Research Article

Promoter Variant of PIK3C3 Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients

Table 3

Case-control association of rs3813065 with SLE in African- and European-American subjects.

MAFOR (C allele)95 CI 𝑃 value

AA cases0.320 1.070.82–1.38.63
AA controls0.380

EA cases0.155 0.650.40–1.06.09
EA controls0.115

MAF: minor allele frequency, OR: odds ratio for association of the C allele in SLE cases as compared to controls in each ancestral background, and 95 CI = 95% confidence interval of the odds ratio.