Identification of an MSI-H Tumor-Specific Cytotoxic T Cell Epitope Generated by the (1) Frame of U79260(FTO)
Figure 3
Target inhibition. FSP11 specificity and HLA-A0201 restriction of target cell lysis of FSP11-specific T cells were tested at two different cell ratios (, ) in the presence of an excess of unlabeled target cells (CD40 Bs pulsed with either FSP11 (square) or control peptide MP (diamond)) at an unlabeled: labeled target cell ratio of ). Displayed is the percentage of labeled and FSP11-loaded CD40 Bs killed by the FSP11-specific T cells. A representative experiment of three is shown. Analysis was performed after a 6-hour incubation period.