Temporal Adaptive Changes in Contractility and Fatigability of Diaphragm Muscles from Streptozotocin-Diabetic Rats

Figure 1

Original raw digital tracing of a control DPH muscle strip showing our intact contractility protocol. This intact contractility record shows the last 4 minutes of equilibration (Equil), followed by the fatiguing stimulation period (Fatigue, 5 minutes) and by the recovery period. During Equil and Recovery, the muscle strip was stimulated with tetanic contractions every minute, while during the fatigue period, the muscles were stimulated every second. Calibration bars for this specific experiment are shown. The horizontal bar denotes time in minutes and the vertical bar the relative force in mN produced by the preparation.