Characterization of Recombinant Dengue-2 Virus Derived from a Single Nucleotide Substitution in the 5′ Noncoding Region

Table 2

Temperature sensitivity (ts) phenotype in LLC-MK₂ cell and percent of oral infection and dissemination in Aedes aegypti mosquitoes.

Viruses	ts phenotype (EOP ratio)	Positive IFA head/body (% dissemination) 𝑛=25
D2-16681	1.3	19/24 (79%)
D2-14.5^M	1.7	11/20 (55%)
D2-15.5^M	1.2	7/16 (44%)
D2-57.5^M	1.6	8/19 (42%)