Research Article

JAK3/STAT5/6 Pathway Alterations Are Associated with Immune Deviation in T Cells in Renal Cell Carcinoma Patients

Figure 8

Altered expression of E2F4 in RCC patient CD8+ T cells. CD8+ T cells were surface-labeled with anti-p-p2 7 K I P 1 (red) and anti-E2F4 (green) mAbs and the performance of confocal microscopy analysis. Quantitative analysis of HPF was carried out by confocal microscopy software (Leica, TCS-SP2; Student’s 𝑡 -test, 𝑃 < . 0 5 ). Data are from 1 of 5 experiments, that all gave comparable results.
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