Research Article

Expression and Purification of Z Protein from Junín Virus

Figure 1

Sequence Logos of Arenavirus Z proteins. The upper diagram shows Z protein and the three regions in which it was divided. The other three are sequence logos, in which the X-axis indicates the relative position of amino acids in the multiple alignments. The length of 111 residues is due to the inclusion of gaps in the multiple alignment. The different amino acid domains described in the text are shadowed and the newly proposed domains are underlined. (a) Sequence Logo from all selected arenavirus Z proteins. (b) Sequence Logo from selected New World arenavirus Z proteins (ANM; AMAV-BeAn70563, CPXV-BeAn119303, GTOV-CVH-961104, GTOV-VHF-3990, JUNV-MC2, JUNV-Candid#1, MACV-MARU-222688, MACV-9530537, TACV, LATV-MARU-10924, OLVV-3229, PIRV-VAV488, PIRV-1743, ALLV-CLHP2472, PICV-AN3739, BCNV-A0060209, BCNV-AV-A0070039, WWAV-AV9310135, TAMV-W10777). (c). Sequence Logo from selected Old World arenavirus Z proteins (AVM; LCMV-Clone#13, LCMV-MX, LASV-CSF, LASV-AV, IPPY-DakAnB188, MOBV-Acar3080, MOPV-AN20410, MOPV-Mozambique, Lujo, and Morogoro).
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(a) Arenavirus
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(b) NWA
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(c) OWA