Research Article

Mechanical and Electrophysiological Properties of the Sarcolemma of Muscle Fibers in Two Murine Models of Muscle Dystrophy: Col6a1 and Mdx

Figure 2

AFM topography (contact mode) of fixed fibers: wild type (a), Col6a1 / (b) and mdx (c) fibers. Two sets of foldings with a periodic pattern can be easily recognized in all three fiber types. The periodicity of the greater foldings, likely in phase with Z-line is about 2  𝜇 m, and the distance between the greater and the smaller foldings is about 1  𝜇 m. The profiles reported in the diagrams on the left are obtained along the dashed lines in the 3D images on the right side.
981945.fig.002a
(a)
981945.fig.002b
(b)
981945.fig.002c
(c)