Figure 1: Values of infarction volume for sham-operated rats (first column), 37°C saline-treated FPI rats (second column), and 4°C saline-treated FPI rats (third column). The saline solutions were administered via the jugular vein 3 minutes after the onset of FPI. The data were obtained on day 3 after surgery. Values are mean ± SEM; per group. * versus sham-operated controls; versus 37°C saline-treated FPI rats. Top photomicrographs depicted the representative picture for a sham-operated rat (Sham), an FPI rat (FPI), and an FPI rat treated with brain cooling (FPI + cooling).