Attenuation of Brain Nitrostative and Oxidative Damage by Brain Cooling during Experimental Traumatic Brain Injury

<table>Values of maximal angle animals could cling to an inclined plane for sham-operated rats ((b) first column), 37°C saline-treated FPI rats ((b) second column), and 4°C saline-treated FPI rats ((b) third column). The saline solutions were administered via the jugular vein 3 minutes after the onset of FPI. The data were obtained on day 3 after surgery. Values are mean ± SEM; <svg height="11.125" id="M12" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> per group. <svg height="13.95" id="M13" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.162498 13.95" width="58.162498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus sham-operated controls; <sup>†</sup><svg height="11.375" id="M14" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 50.549999 11.375" width="50.549999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" id="x30"></path></g><g transform="matrix(.017,-0,0,-.017,42.321,11.112)"><path d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8
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</svg> versus 37°C saline-treated FPI rats.</table>

BioMed Research International

fig3

Figure 3

Figure 3: Attenuation of Brain Nitrostative and Oxidative Damage by Brain Cooling during Experimental Traumatic Brain Injury 