Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates

Table 3

Proteins interacting with and inhibiting the deacetylase activity of HDAC6.

Interacting proteins	Substrates affected	Functions involved	References
TPPP/p25	Tubulin	Decrease cell mobility	[59]
CYLD	Tubulin	Cell proliferation	[60]
IIp45	Tubulin (decreases stability of HDAC6)	Cell migration	[61]
Tau	Tubulin	Prevent autophagy	[62]
EGFR	Tubulin (decreases deacetylase activity of HDAC6 by phosphorylation)	Decrease endocytosis and degradation	[63]