Brown Adipose Tissue Can Be Activated or Inhibited within an Hour before ¹⁸F-FDG Injection: A Preliminary Study with MicroPET

Figure 1

Comparison of interscapular BAT uptake in mice receiving different interventions from microPET sagittal images. For visual analysis, microPET images showed that mouse interscapular BAT ¹⁸F-FDG uptake (arrow) varied under different interventions. (c) Cold plus NE interventions showed highest BAT uptake (𝑅=15.64±5.58, 𝑃=2.19×10⁻⁶) compared to (b) cold exposure (𝑅=10.22±4.13, 𝑃=1.96×10⁻⁴) and (a) control (𝑅=4.08±1.32), while (d) warming (𝑅=2.13±0.43, 𝑃=.001) and (e) propranolol (𝑅=1.30±0.16, 𝑃=.027) showed decreased BAT uptake in cold pre-exposure mice.

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