Myelodysplastic Syndrome and Histone Deacetylase Inhibitors: “To Be or Not to Be Acetylated”?

<table>Overview of transcriptional regulation by epigenetic mechanisms involving DNA methylation and histone acetylation. Abbreviations: DNMT: DNA methyl transferase; HDAC(i): histone deacetylase (inhibitor); HMT: histone methyltransferase; HP1: heterochromatin protein 1.</table>

BioMed Research International

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Figure 2

Figure 2: Myelodysplastic Syndrome and Histone Deacetylase Inhibitors: “To Be or Not to Be Acetylated”? 