BioMed Research International / 2011 / Article / Fig 2

Review Article

Myelodysplastic Syndrome and Histone Deacetylase Inhibitors: “To Be or Not to Be Acetylated”?

Figure 2

Overview of transcriptional regulation by epigenetic mechanisms involving DNA methylation and histone acetylation. Abbreviations: DNMT: DNA methyl transferase; HDAC(i): histone deacetylase (inhibitor); HMT: histone methyltransferase; HP1: heterochromatin protein 1.