Cytogenetic Instability in Childhood Acute Lymphoblastic Leukemia Survivors
Figure 1
Mean frequency of gene fusions in peripheral lymphocytes from ALL survivors analyzed months or year(s) after therapy completion (black boxes) and healthy donors (white boxes). In the case of MLL fusions the group of survivors was subdivided into patients treated with topoisomerase II inhibitors (grey box) and patients treated without the inclusion of such drugs in the treatment protocol (black box). . Data for ETV6/RUNX1 and MLL was taken from Brassesco et al. [20] and [19], respectively.
