Development of ⁶⁸Ga-Glycopeptide as an Imaging Probe for Tumor Angiogenesis

Table 2

Biodistribution of FDG in breast tumor-bearing rats. % of injected dose per gram of tissue weight (𝑛=3/time, interval, i.v.)*.

	30 min	60 min	120 min
Blood	0.40 ± 0.04	0.13 ± 0.01	0.06 ± 0.00
Heart	1.57 ± 0.06	1.38 ± 0.13	1.08 ± 0.07
Lung	0.55 ± 0.06	0.42 ± 0.02	0.46 ± 0.03
Thyroid	1.07 ± 0.08	1.04 ± 0.04	1.05 ± 0.07
Pancreas	0.26 ± 0.03	0.21 ± 0.01	0.20 ± 0.02
Liver	0.40 ± 0.05	0.16 ± 0.01	0.13 ± 0.01
Spleen	0.82 ± 0.08	0.74 ± 0.03	0.86 ± 0.07
Kidney	0.71 ± 0.05	0.37 ± 0.01	0.24 ± 0.02
Stomach	0.61 ± 0.08	0.44 ± 0.03	0.39 ± 0.03
Intestine	0.69 ± 0.07	0.53 ± 0.03	0.52 ± 0.02
Uterus	0.51 ± 0.04	0.42 ± 0.03	0.41 ± 0.03
Tumor	2.13 ± 0.11	2.49 ± 0.08	2.03 ± 0.18
Muscle	0.33 ± 0.04	0.34 ± 0.03	0.74 ± 0.02
Bone	0.33 ± 0.04	0.44 ± 0.06	0.50 ± 0.03
Brain	2.00 ± 0.15	1.99 ± 0.05	1.39 ± 0.09
Tumor/blood	5.19 ± 0.38	19.78 ± 1.37	34.37 ± 1.76
Tumor/muscle	5.88 ± 0.57	7.54 ± 0.56	2.87 ± 0.24

* Value shown represent the mean ± standard deviation of data from 3 animals at (Count at 460–560 keV window).