Using Rhodamine 123 Accumulation in CD<sup>8+</sup> Cells as a Surrogate Indicator to Study the P-Glycoprotein Modulating Effect of Cepharanthine Hydrochloride In Vivo

<table>Rho123 accumulations in CD8<sup>+</sup> cells <i>ex vivo</i>, where the grey lines stand for cells treated with Rho123 plus the vehicle and it was set as the control in the four sub-figures and the black lines represent cells treated with Rho123 in the presence of various concentrations reversors: A. VER 5.0 <i><i>μ</i></i>M, B. CH 2.5 <i><i>μ</i></i>M, C. CH 5.0 <i><i>μ</i></i>M, D. CH 10.0 <i><i>μ</i></i>M. This figure is representative of at least four independent experiments.</table>

BioMed Research International

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Figure 4

Figure 4: Using Rhodamine 123 Accumulation in CD<sup>8+</sup> Cells as a Surrogate Indicator to Study the P-Glycoprotein Modulating Effect of Cepharanthine Hydrochloride In Vivo 

Figure 4 | Using Rhodamine 123 Accumulation in CD8+ Cells as a Surrogate Indicator to Study the P-Glycoprotein Modulating Effect of Cepharanthine Hydrochloride In Vivo 