Using Rhodamine 123 Accumulation in CD8+ Cells as a Surrogate Indicator to Study the P-Glycoprotein Modulating Effect of Cepharanthine Hydrochloride In Vivo
Table 1
The Tumor inhibition of the Hca/FAP solid tumor after treatment.
Treatment groups
Avg. tumor weights (mg)
%Tumor growth inhibition
Mortality
FAP+CH 10.0 mg/kg
248.0 ± 88.0*
71.4%
0/10
FAP+CH 5.0 mg/kg
364.0 ± 82.2*
57.9%
0/10
FAP+CH 2.5 mg/kg
479.0 ± 96.8*□
44.7%
0/10
FAP+VER 2.5 mg/kg
482.8 ± 59.4*□
44.2%
2/10
FAP
479.0 ± 187.5*
44.7%
0/10
CH 10.0 mg/kg
689.0 ± 104.8*
20.4%
0/10
Control
866.0 ± 153.3
—
0/10
, different from the control, □no significant difference from each other ().
