Identification of NF-κB Modulation Capabilities within Human Intestinal Commensal Bacteria
Figure 4
Correlation between butyrate or propionate concentration of the bacteria CM and NF-κB activity. NF-κB activity measured in HT-29 in response to cotreatment with bacteria CM and TNF-α (10 ng/mL) based on the amount of butyrate (a) and propionate (b) present in each bacteria CM. NF-κB activity is expressed as a relative percentage (values from Figure 2). Butyrate and propionate amounts were determined by HPLC and expressed in mM. A Spearman correlation test was performed: Butyrate versus NF-κB activity: (). Propionate versus NF-κB activity: (). Propionate (Bacteroidetes only) versus NF-κB activity: ().
