Culture Environment-Induced Pluripotency of SACK-Expanded Tissue Stem Cells
Figure 6
Reprogrammed cell clones derived from SACK-D pancreatic stem cell strain mPanstra-12 form teratomas in immunodeficient mice. Shown are micrographs of hematoxylin-and-eosin-stained tissue sections from subcutaneous tumors formed from mESCs or reprogrammed 12-KOSR-Xn-89 (AP+) and 12-KOSR-Xn-83 (AP−) cell clones. The corresponding embryonic germ layer of each histological example is indicated. ca, cartilage; mu, muscle; de, digestive tract epithelium; nc, neurectoderm; ne, nerve. μm.
