Research Article

Antinociceptive Activity of the Chloroform Fraction of Dioclea virgata (Rich.) Amshoff (Fabaceae) in Mice

Table 1

Summary of multiple tests conducted with CFDv and their results.

MethodsResults

General testsBehavioral pharmacological screeningCNS-depressant activity
Pentobarbital-induced sleeping timeThere was no effect on total sleeping time
Rota Rod testAbsence motor abnormality or neurotoxicity
Open-field testSedative action

Specific tests (antinociceptive activity)Acetic acid-induced abdominal writhingAntinociceptive activity
Formalin testActivity may probably be mediated in the CNS level