A New Microarray System to Detect Streptococcus pneumoniae Serotypes

Table 2

Twenty-three groups distinguished in this study and targeted glycosyltransferase genes.

Group name	Targeted GT genes in cps locus (probe number^a)
1	wchB (1,2,3)	wchD (4,5,6)
2	wchF (7,8,9)	wchG (10,11,12)	wchH (13,14,15)	wchI (16,17,18)
3	wchE (19,20,21)
4	wciJ (22,23,24)	wciK (25,26,27)	wciL (28,29,30)
5	wciJ (31,23,24)	whaC (32,33,34)	whaD (35,36,37)
6A/6B	wciN (38,39,40)	wciP (41,42,43)
7F/7A	wchF (44,45,46)	wcwA (47,48,49)	wcwF (50,51,52)	wcwG (53,54,55)	wcwH (56,57,58)
8	wciR (59,60,61)	wciR (62,63,64)	wciS (65,66,67)	wciT (68,69,70)
9A/9V	wchO (71,72,73,74)	wcjA (75,76,77)	wcjB (78,84,85)	WcjC (81,82,83)
9L/9N	wchO (71,72,73,74)	wcjA (75,76,77)	wcjB (78,79,80)	wcjC (81,82,83)
10A	wciB (86,87,8)	wcrC (89,90,91)	wcrD (92,93,94)	wciF (95,96,97)	wcrG (98,99,100)
11A/11D	wchK (101,102,103)	wcyK (104,105,106)	wcrL (107,108,109)
12F/12A/; 12B/44/46	wciJ (110,111,112)	wcxB (113,114,115)	wcxD (116,117,118)	wcxE (119,120,121)	wcxF (122,123,124)
14	wchK (125,126,127)	wchL (128,129,130,131)	wchM (132,133,1334)	wchN (135,136,137)
15B/15C	wchK (138,139,125)	wchL (128,140,141,131)	wchM (142,143)	wchN (135)
17F	wchF (144,145,146)	abp1 (147,148,149)	wciP (150,151,152)	wcrV (153,154,155)
18B/18C	wchF (156,157)	wciU (158,159,160)	wciV (161,162,163)	wciW (164,165,166)
19F	wchO (167,72,168,169)	wchQ (171,172,173)
19A	wchO (71,170,73,74)	wchQ (171,172,173)
20	wciB (174,175,176)	whaJ (177,178,179)	wciL (180,181,182)	wcwK (183,184,185)	wciD (186,187,188)	whaF (189,190,191)
22F/22A	wchF (7,8,192,193)	wcwA (48,49,194)	wcwV (195,196,197)	whaB (198,199,200)
23F	wchF (144,156,145,193,201)	wchV (202,203,204)	wchW (205,206,207)
33F/33A/; 37	wciB (208,209,210)	wciC (211,212,213)	wciD (214,215,216)	wciE (217,218,219)	wciF (220,221,222)

Explanatory notes: ^aProbes containing 60-bp oligonucleotides were designed and named as 1, 2, 3 etc from Group 1. The name of each GT gene (wchB etc) was derived from the Sanger Institute.