Experimentally Approaching the ICU: Monitoring Outcome-Based Responses in the Two-Hit Mouse Model of Posttraumatic Sepsis

Figure 6

Retrospective comparison of red blood cell platelet count, and hemoglobin concentration in dying (DIE) versus surviving (SUR) animals after-CLP. 3-month-old female mice were subjected to trauma/hemorrhage followed by polymicrobial CLP-induced sepsis. Displayed values were compared between DIE and SUR group 6 h (DIE at least 𝑛=30, SUR at least 𝑛=32), 24 h (DIE at least 𝑛=28, SUR at least 𝑛=31), 48 h (DIE at least 𝑛=16, SUR at least 𝑛=31), 72 h (DIE at least 𝑛=11, SUR at least 𝑛=32), and 96 h (SUR at least 𝑛=26 for all parameters) after-CLP. Dotted lines represent normal values. *𝑃<.05.

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