Experimentally Approaching the ICU: Monitoring Outcome-Based Responses in the Two-Hit Mouse Model of Posttraumatic Sepsis

Figure 7

Retrospective comparison of neutrophil and lymphocyte count in dying (DIE) versus surviving (SUR) animals after-CLP. 3-month-old female mice were subjected to trauma/hemorrhage followed by polymicrobial CLP-induced sepsis. Displayed values were compared between DIE and SUR groups 6 h (DIE 𝑛=31, SUR 𝑛=33), 24 h (DIE 𝑛=29, SUR 𝑛=34), 48 h (DIE 𝑛=18, SUR 𝑛=32), 72 h (DIE 𝑛=12, SUR 𝑛=32), and 96 h (SUR 𝑛=28) after-CLP. Dotted lines represent normal values. *𝑃<.05.

(a)

(b)