Effects of a Tumor Necrosis Factor-α Antagonist on Experimentally Induced Rhinosinusitis

Table 1

Histopathological changes in nasal mucosa (mean ± SD).

Group	Absorbance		Mucosal thickness (mm)		PAS-stained area (%)
	1st day	4th day	1st day	4th day	1st day	4th day
Saline	0.09 ± 0.04	0.10 ± 0.02	1.01 ± 0.26	1.21 ± 0.67	16.54 ± 1.93	16.39 ± 1.34
LPS	0.17 ± 0.03	0.21 ± 0.01	2.11 ± 1.27	2.26 ± 1.27	22.24 ± 2.90	24.78 ± 3.61
LPS + sTNFRI	0.12 ± 0.01	0.12 ± 0.02	1.32 ± 0.66	1.22 ± 0.45	15.81 ± 1.64	16.24 ± 3.75
LPS + antibiotic	0.12 ± 0.01	0.19 ± 0.01	1.52 ± 0.79	1.97 ± 0.93	14.60 ± 2.75	16.82 ± 1.06
LPS + sTNFRI + antibiotic	0.11 ± 0.02	0.11 ± 0.01	1.17 ± 0.79	1.31 ± 0.57	16.39 ± 1.34	16.31 ± 4.81