Review Article
Inflammatory Cytokines in Systemic Lupus Erythematosus
Table 1
IL-17 exerts effects on several cell types and tissues.
| T cells | Induces production of proinflammatory IL-6, IL-1beta, and IL-21, providing a feedback loop [148] | Enhances recruitment of T cells to inflamed tissue [155] |
| B cells | Drives B-cell differentiation into plasma cells and production of autoantibodies [158, 159] |
| Monocytes | Enhances migration to inflamed tissue [173] |
| Epithelial/ endothelial cells | Induces increased production of chemokines and upregulation of adhesion molecules [152] |
| Neutrophils | Enhances migration to inflamed tissue [154] |
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