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Journal of Biomedicine and Biotechnology
Volume 2011, Article ID 474632, 15 pages
Research Article

MicroRNA Gene Dosage Alterations and Drug Response in Lung Cancer

1British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3
2Research Institute, Nationwide Children’s Hospital, Columbus, OH 43205-2664, USA

Received 1 November 2010; Accepted 27 January 2011

Academic Editor: E. Felip

Copyright © 2011 Katey S. S. Enfield et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Table 1 - List of 18 drugs analyzed in this study.

Supplemental Table 2 - List of lung cancer cell lines with either SNP 6.0 copy number, miRNA expression, or IC50 response.

Supplemental Table 3 - Summary of copy number alteration comparisons for all miRNAs across all drugs.

Supplemental Table 4 - miRNAs significantly differentially expressed across 18 drugs.

Supplemental Table 5 - mRNA targets found by TargetScan and TargetSpy for the four identified miRNAs.

  1. Supplementary Tables