Research Article

HKC: An Algorithm to Predict Protein Complexes in Protein-Protein Interaction Networks

Figure 5

Precision versus Recall plots of all WCODE and HKC results with different parameters on various data sets. (a) Input data set: MIPS, benchmark: complexcat. (b) Input data set: MIPS, benchmark: Gavin. (c) Input data set: SGD-MC, benchmark: complexcat. (d) Input data set: SGD-MC, benchmark: Gavin. For all four cases, the data points resulted by HKC are located in the upper right portion of the plot, corresponding to high values of F-measure, while most of the data points resulted by MCODE are located in the lower left part of the plot. Furthermore, the data points resulted by HKC are much more centralized than MCODE.
480294.fig.005a
(a)
480294.fig.005b
(b)
480294.fig.005c
(c)
480294.fig.005d
(d)