Computational Vaccinology: An Important Strategy to Discover New Potential S. mansoni Vaccine Candidates

Figure 1

Most common methodology for investigation of potential vaccine candidates. Possible targets are predicted based on sequences databases and proteomic analysis. Further bioinformatic studies provide detailed information about protein primary structure, topology, subcellular localization, conserved domains, HLA-peptide binding, and posttranslational modifications.* [7–10].