A Novel Animal Model of Hippocampal Cognitive Deficits, Slow Neurodegeneration, and Neuroregeneration
Figure 3
Pilot data assessing the electrophysiological response of the dentate gyrus after 10 weeks of adrenalectomy (ADX) followed by one-week of CORT replacement, all ADX rats were on CORT replacement at the time of recording. (a) Chronic ADX resulted in a significantly attenuated fEPSP slope relative to control rats. (b) A tendency for ADX rats to have a lower population spike amplitude compared to intact controls was apparent. Error bars represent standard error of the mean.
