Transcription Factor Sp1 Is Involved in Expressional Regulation of Coxsackie and Adenovirus Receptor in Cancer Cells
Figure 6
Effect of Sp1 binding on infectivity of adenoviral containing β-gal. (a) MCF-7 cells were treated by TSA with or without pretreatment of mithramycin and infected by Ad-β-gal (50 MOI). Photographs of the cells stained for β-galactosidase activity. (a) represents whole cells and some part of the whole cells under a higher magnification, respectively, scale bar: 50 μm. (b) Quantitation of β-galactosidase-positive cells after the virus infection. β-galactosidase-positive cells were counted from three nonoverlapping fields of the cells treated as indicated. Bars represent the mean ± SD.
