BioMed Research International / 2011 / Article / Fig 2

Review Article

Natural Killer Cells in Human Cancer: From Biological Functions to Clinical Applications

Figure 2

NK cell tumor immunity and alloimmunity after allogeneic ACT. Autologous NK cell killing is inhibited when self-class I MHC on tumor cells is recognized. In allogeneic ACT, NK cell KIR-mismatch is implicated both in GVHD and in mediating of a GVL effect.

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