In Vivo Imaging of Particle-Induced Inflammation and Osteolysis in the Calvariae of NF𝜅B/Luciferase Transgenic Mice

Figure 2

(a) In vivo imaging analysis was performed on the indicated days after loading of 5 mg PE. (b) Quantitative analysis of luminescence in (a) (𝑛=3 per bar, Mean±SD, ^∗𝑃<.05, ^∗∗𝑃<.001, ^∗∗∗𝑃<.0001, 5 mg PE versus sham at each time point). (c) In vivo imaging analysis performed on day 7 after loading of the indicated amounts of PE. (d) Quantitative analysis of luminescence in (c) (𝑛=3 per bar, Mean±SD, ^∗𝑃=.0005, ^∗∗𝑃<.0001 versus sham).

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