In Vivo Imaging of Particle-Induced Inflammation and Osteolysis in the Calvariae of NF𝜅B/Luciferase Transgenic Mice

Figure 5

(a) Levels of bone resorption parameters (N.Oc/BS, Oc.S/BS, and ES/BS) as assessed by bone histomorphometry in calvarial tissues retrieved on day 7 after PE loading (𝑛=4 per bar, Mean±SD, ^∗𝑃<.05, ^∗∗𝑃<.005 versus sham). (b) Correlation between total influx and levels of bone resorption parameters. The correlation coefficient and 𝑃 values were 𝑟=0.848, 𝑃<.0005 for N.Oc/BS; 𝑟=0.862, 𝑃<.0001 for Oc.S/BS; 𝑟=0.837, 𝑃<.0005 for ES/BS.

(a)

(b)