Review Article
Clinical Therapeutics in Pregnancy
Table 1
Pregnancy-induced physiologic changes during near term.
| System [ref.] | Parameter | Non pregnant | Pregnant |
| Cardiovascular [18, 19] | Cardiac output (L/min) | 4.0 | 7.0 | | Heart rate (beats per min) | 70 | 90 | | Stroke volume (mL) | 65 | 85 | | Plasma volume (L) | 2.6 | 3.5 | | Colloid osmotic pressure (mmHg) | 22.0 | 18.2 | | Total peripheral arterial resistance (dyne s cmā5) | 1530 | 1210 |
| Respiratory [20] | Total lung capacity (mL) | 4225 | 4080 | | Residual volume (mL) | 965 | 770 | | Tidal volume (mL) | 485 | 680 | | Minute O2 uptake | 201 | 265 |
| Liver [21] | Portal vein blood flow (L/min) | 1.25 | 1.92 | | Hepatic artery blood flow (L/min) | 0.57 | 1.06* |
| Renal [22] | Glomerular filtration rate (mL/min) | 97 | 144 | | Creatinine (mg/dL) | 0.7 | 0.5 |
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*Difference was not statistically significant.
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