Role of Positive Selection in Functional Divergence of Mammalian Neuronal Apoptosis Inhibitor Proteins during Evolution
Figure 1
Manually corrected alignments. (a) Alignments before manual correction; (b) Alignments after manual correction. Alignment were constructed using Clustal X and modified with Boxshade (http://www.ch.embnet.org/software/BOX_form.html). Functional domains are designed as BIR, P-loop NTPase, and LRP. “*” indicated highly conserved residues. Functional (f) or structural (s) residues (f indicates highly conserved and exposed, s indicates highly conserves and buried); “#” indicates amino-acids had changed during the evolution.
