Research Article

Muscle Atrophy and Motor Neuron Degeneration in Human NEDL1 Transgenic Mice

Figure 2

Overexpression of hNEDL1 affected the locomotion and rotarod performance. (a) Behavior (locomotion) in the mice was evaluated; each value (counts per 10 min) is the mean ± SEM ( ; ; ). (b) The rotarod performance of wild-type (white bar: ) and hNEDL1-Tg mice (black bar: ) from the age of six mounths to fifteen months. Data are mean ± SEM ( ; ).
831092.fig.002a
(a)
831092.fig.002b
(b)