A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, and In Vivo Antitumor Efficacy and Safety
Figure 4
Tumor growth inhibition by PTX injection or PTX microemulsion. BALB/C mice were inoculated s.c. with OVCAR-3 cells (a) or A-549 cells (b) and treated with 5% glucose, PTX injection or PTX microemulsion (15 mg/kg, i.v., q4d4, every 4 days for four doses), respectively. Tumor size was measured with calipers twice per week. Results are given as means ± S.D. (). ** versus 5% glucose infusion as control.
