A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, and <i>In Vivo </i> Antitumor Efficacy and Safety

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Grade 1/+</td><td align="center">Grade 2/++</td><td align="center">Grade 3/+++</td><td align="center">Grade 4/++++</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">Mania</td><td align="center">Drowsiness</td><td align="center">Angioedema</td><td align="center">Life-threatening</td></tr><tr><td align="left">Licking nose</td><td align="center">Rash/flushing/urticaria</td><td align="center">Gatism</td><td align="center">Death</td></tr><tr><td align="left">Transient flushing or rash</td><td align="center">Mucous membrane hyperemia</td><td align="center">Vomiting</td><td align="center"></td></tr><tr><td align="left">Head shaking</td><td align="center">Dyspnea</td><td align="center"></td><td align="center"></td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

BioMed Research International

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Table 1

Table 1: A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, and <i>In Vivo </i> Antitumor Efficacy and Safety 

Table 1 | A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, and In Vivo  Antitumor Efficacy and Safety 