A New Normalizing Algorithm for BAC CGH Arrays with Quality Control Metrics

Table 2

Table comparing the median MAD values on the X chromosome for each of the normalization methods. From this metric, we see that the “SmoothArray” normalization procedure provides the optimal noise reduction for probes on the X chromosome.

Raw	“SmoothArray”	Grid loess	Quantile normalization	Global median	Background subtraction
0.1465	0.1139	0.1215	0.1468	0.1465	0.1675