Antiobesity and Hypoglycaemic Effects of Aqueous Extract of Ibervillea sonorae in Mice Fed a High-Fat Diet with Fructose

Table 3

Glycaemia and lipid profile in male mice fed HFF and/or IS for 8 weeks.

	Control	IS 400 mg/kg	HFF	HFF + IS 100 mg/kg	HFF + IS 200 mg/kg	HFF + IS 400 mg/kg
Triglycerides (mmol/L)	0.9 ± 0.05	1.15 ± 0.2^a	1.7 ± 0.2^a	1.36 ± 0.2	1.2 ± 0.11	0.96 ± 0.11^b
Cholesterol (mmol/L)	18.6 ± 0.4	29 ± 2.2^a	35 ± 2.8^a	38.8 ± 3.8^a	32.3 ± 3.8^a	28.4 ± 1.4^b
HDL-C (mmol/L)	9.5 ± 0.6	7.7 ± 1.6^b	20.8 ± 1.4^a	16.4 ± 1.7^a	16.1 ± 0.5^a	16.4 ± 1.4^a
LDL-C (mmol/L)	12.1 ± 1.7	21.8 ± 6.1^a	15.0 ± 3.2	23.1 ± 4.5^a	16.7 ± 0.01	12.40 ± 1.4
Glycaemia (mg/dL)	84.4 ± 6.7	96 ± 7.1	169.8 ± 13.9^a	141 ± 21.4^a	128.3 ± 13.2^a	91.8 ± 7.1^b
Atherogenic index	0.9 ± 0.2	2.8 ± 1.1^a	0.7 ± 0.9	1.4 ± 0.7	1.0 ± 0.09	0.7 ± 1.2

Data are mean ± S.E. HFF: high fat and fructose; IS: Ibervillea sonorae; a: significant difference compared to Control; b: significant difference compared to HFF, 𝑃<0.05 (one-way ANOVA, Tukey’s post hoc test).