Surgical Approaches to Create Murine Models of Human Wound Healing

Table 2

Surgical mouse models of cutaneous disease with select references.

Mouse Model	Human Disease Relevance	Select References
Excisional Wound	Diabetes and obesity	[31, 65, 66]
	Aging	[67, 68]
	Obesity	[69]
Ischemic Flap	Diabetes	[35]
	Aging	[34]
Pressure Ulcer	Diabetes	[37]
	Decubitus ulcers	[38, 39]
Mechanical Load	Hypertrophic scar formation	[29]
Parabiosis	Diabetes, obesity	[61, 62]
	Ischemic wounds	[59]
	Scleroderma	[63]
	Aging	[64]
Dorsal Skin Fold Chamber	Arteriovenous malformations	[56]
Xenografting	Donor graft integration	[70]
	Wound remodeling	[71]