Table 1: Quantitative data between control (wild-type) and dystrophic (mdx) TA muscles without and with injury. Except for RD, all the calculated water diffusion characteristics were significantly altered ( ) after injury, and to a greater extent in mdx muscles. There was a trend toward increased RD, but this was not significant (NS) at .

mdx noninjured versus wt noninjuredwt injured versus noninjuredmdx injured versus wt injuredmdx injured versus noninjured

Whole MD (mm2/s)NSNS versus ) versus )
Proximal MD (mm2/s)NSNS versus )NS
Middle MD (mm2/s)NSNS versus )NS
Distal MD (mm2/s)NSNSNSNS
Whole AD (mm2/s)NSNS versus ) versus )
Proximal AD (mm2/s)NSNS versus ) versus )
Middle AD (mm2/s)NSNS versus ) versus )
Distal AD (mm2/s)NSNSNSNS
Whole FANSNS versus ) versus )
Proximal FANSNS versus ) versus )
Middle FANSNS versus ) versus )
Whole RD (mm2/s)NSNSNSNS
Proximal RD (mm2/s)NSNSNSNS
Middle RD (mm2/s)NSNSNSNS
Distal RD (mm2/s)NSNSNSNS
Whole T2 (ms)NSNSNSNS
Proximal T2 (ms)NSNS versus )NS
Middle T2 (ms)NSNSNSNS
Distal T2 (ms)NSNSNSNS

Explanation of DTI parameters (apply to all but the last 4 lines, which report data for T2): MD: mean diffusivity; measure of total diffusion within a voxel; AD: axial diffusivity; diffusion along the longitudinal axis; FA: fractional anisotropy; the fraction of unidirectional diffusion; RD: radial diffusivity; diffusion occurring perpendicular to a track; T2: a time constant describing the exponential decay of signal.