Table 2: Discriminative influence of the proposed features based on the F-score values.

Feature labelF-ScoreRank

Number of nuclei within the acinar structure0.054714
Elongation of the acinar structure0.11226
Ratio between the hollow lumen and acinar structure areas0.16024
Internal integrin 𝛼 6 Density0.12055
Density of integrin 𝛼 6 inside the 30% circle0.062011
Density of integrin 𝛼 6 inside the 40% circle0.061112
Density of integrin 𝛼 6 inside the 50% circle0.08859
Density of integrin 𝛼 6 inside the 60% circle0.09538
Density of integrin 𝛼 6 inside the 70% circle0.059813
Continuity of integrin 𝛼 6 along the basal membrane0.57251
Amount of integrin 𝛼 6 colocalized with integrin 𝛼 3 0.033715
Continuity of integrin 𝛼 3 along the basal membrane0.10467
Total integrin 𝛼 3 density0.26513
Amount of integrin 𝛼 3 colocalized with integrin 𝛼 6 0.35262
Density of integrin 𝛼 3 in the exterior of the hollow lumen0.071610