Computer-Based Annotation of Putative AraC/XylS-Family Transcription Factors of Known Structure but Unknown Function

Figure 1

Structural alignment of three putative AraC/XylS family members (PDB codes: 3mn2, 3oio, and 3oou; gold ribbons) with MarA (PDB code: 1bl0; red ribbons). The DNA molecule of the MarA structure is shown for illustration (gray); however 3mn2, 3oio, and 3oou were crystallized without DNA. Numbers of α-helices are given next to the respective α-helix. The alignment was generated with SALIGN [16] and the figure was created with the Molecular Operating Environment (MOE) [17].