BioMed Research International / 2012 / Article / Fig 8

Research Article

MOfinder: A Novel Algorithm for Detecting Overlapping Modules from Protein-Protein Interaction Network

Figure 8

The module-module communication network and functional characterization. The network is built by GenePro 2.5.2b [39]. Each node represents a module, and the edge between two nodes means these two modules share at least one protein. Edge color represents the GO similarity: the values between 0 and 1 are painted with a pink/blue color gradient, and gray means lack of GO annotation. (a) The module module communication network. In the pie plot of each node, the color means function: red is cancer related, yellow is immune related, and blue is other function. The size of sector means the percentage of each type of functional proteins. (b) Functional characterization of each module in the largest cluster (rounded by rectangle of dotted line). Modules are painted green (if there is a GO annotation) or gray (lack of GO annotation).

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