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Journal of Biomedicine and Biotechnology
Volume 2012, Article ID 134031, 11 pages
Research Article

Distinct Effects of Contraction-Induced Injury In Vivo on Four Different Murine Models of Dysferlinopathy

Department of Physiology, University of Maryland School of Medicine, 655 W. Baltimore Street, Baltimore, MD 21201, USA

Received 27 June 2011; Accepted 27 September 2011

Academic Editor: Aikaterini Kontrogianni-Konstantopoulos

Copyright © 2012 Joseph A. Roche et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1. Data from multiple sets of B6.A/J mice. Due the high level of variability seen in B6.A/J animals, we performed physiological measurements on additional sets of animals. Data from 24 animals in 4 different sets are presented.

Figure S2. Comparison of torque data between multiple sets of B6.A/J, and a single set of C57Bl/6J and A/J mice. With increased sample size (N=24), B6.A/J were statistically indistinguishable from C57Bl/6J and A/J at D0, but they were different from both these strains at D3 (upper histogram and table), and were more variable (lower histogram).

  1. Supplementary Material