Potential Role of Kringle-Integrin Interaction in Plasmin and uPA Actions (A Hypothesis)
Figure 5
A model of integrin, uPA kringle, and uPAR complex. We performed docking simulation of the interaction between uPA kringle (PDB code 2URK) and integrin (PDB code 1L5G) using Autodock3. The simulation predicted the poses in which uPA kringle interacts with . The uPA kringle-integrin complex was superposed with the ATF-uPAR complex (PDB code 2I9B).
