Transfer of Bone-Marrow-Derived Mesenchymal Stem Cells Influences Vascular Remodeling and Calcification after Balloon Injury in Hyperlipidemic Rats

<table>Effect of BM-MSCs on vascular remodeling after balloon angioplasty. Vascular tissues were stained with hematoxylin-eosin for morphometric analysis. (a) Ruptured internal elastic lamina was present at the site of lesion, whereas splitting of the intima was replaced with significant neointimal formation after balloon angioplasty. (b) Histomorphometric parameters including LA, IELA, EELA, remodeling index, neointimal area, and percentage of stenosis indicated vascular negative remodeling. The scale bar indicated 500 <i>μ</i>m (top row, 40x) and 100 <i>μ</i>m (bottom row, 400x), respectively. The data were expressed as means ± SEM. <svg height="10.9125" id="M28" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 35.099998 10.9125" width="35.099998" xmlns="http://www.w3.org/2000/svg">
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</svg> per group. *<svg height="11.25" id="M29" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 56.150002 11.25" width="56.150002" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
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</svg> versus control, <sup>#</sup><svg height="11.25" id="M30" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 56.150002 11.25" width="56.150002" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
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BioMed Research International

fig2

Figure 2

Figure 2: Transfer of Bone-Marrow-Derived Mesenchymal Stem Cells Influences Vascular Remodeling and Calcification after Balloon Injury in Hyperlipidemic Rats 

Figure 2 | Transfer of Bone-Marrow-Derived Mesenchymal Stem Cells Influences Vascular Remodeling and Calcification after Balloon Injury in Hyperlipidemic Rats 