Research Article

Transfer of Bone-Marrow-Derived Mesenchymal Stem Cells Influences Vascular Remodeling and Calcification after Balloon Injury in Hyperlipidemic Rats

Figure 3

Effect of BM-MSCs on neointimal formation after balloon angioplasty. (a) The PCNA expression was evaluated immunohistochemically to investigate proliferative activity in vascular tissue. PCNA-stained nuclei were detected in the neointimal and medial layers of vascular wall at 6 weeks after vascular denudation. (b) PCNA index was significantly increased after BM-MSCs transplantation compared with injury group. The data were expressed as means ± SEM. 𝑛 = 8 per group. * 𝑃 < 0 . 0 5 versus control, # 𝑃 < 0 . 0 5 versus injury group.
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(a)
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(b)