Figure 3: Effect of BM-MSCs on neointimal formation after balloon angioplasty. (a) The PCNA expression was evaluated immunohistochemically to investigate proliferative activity in vascular tissue. PCNA-stained nuclei were detected in the neointimal and medial layers of vascular wall at 6 weeks after vascular denudation. (b) PCNA index was significantly increased after BM-MSCs transplantation compared with injury group. The data were expressed as means ± SEM. per group. * versus control, # versus injury group.